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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2806
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hmox1
Name: heme oxygenase 1
Acc ID: CHEBI:67897
Term: farrerol
Definition: An organic molecular entity that has formula C17H16O5.
Chemical ID: MESH:C015881
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:107176480464CTDfarrerol results in increased expression of HMOX1 mRNA, farrerol results in increased expression of HMOX1 protein

PMID:26111761
multiple interactionsISORGD:107176480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [farrerol results in increased expression of HMOX1 protein], Dithiothreitol inhibits the reaction [farrerol results in increased expression of HMOX1 protein], Mercaptoethanol inhibits the reaction [farrerol results in increased expression of HMOX1 protein], NFE2L2 protein promotes the reaction [farrerol results in increased expression of HMOX1 protein], SB 203580 inhibits the reaction [farrerol results in increased expression of HMOX1 protein], U 0126 inhibits the reaction [farrerol results in increased expression of HMOX1 protein]

PMID:26111761
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.