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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2806
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hmox1
Name: heme oxygenase 1
Acc ID: CHEBI:6498
Term: lipoxin A4
Definition: A C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds.
Chemical ID: MESH:C040527
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hmox1increases expressionEXP 6480464CTDlipoxin A4 results in increased expression of HMOX1 mRNA; lipoxin A4 results in increased expression of HMOX1 proteinPMID:23826208
Hmox1multiple interactionsEXP 6480464CTDlipoxin A4 promotes the reaction [NFE2L2 protein binds to HMOX1 enhancer]PMID:23826208
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