GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hmox1 | increases expression | ISO | Hmox1 (Mus musculus) | 6480464 | CTD | cadmium sulfate results in increased expression of HMOX1 protein | PMID:14687664 | Hmox1 | increases expression | ISO | HMOX1 (Homo sapiens) | 6480464 | CTD | cadmium sulfate results in increased expression of HMOX1 mRNA | PMID:17244614 PMID:21783983 | Hmox1 | multiple interactions | ISO | Hmox1 (Mus musculus) | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cadmium sulfate results in increased expression of HMOX1 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [cadmium sulfate results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [cadmium sulfate results in increased expression of HMOX1 protein] | PMID:14687664 | Hmox1 | multiple interactions | ISO | HMOX1 (Homo sapiens) | 6480464 | CTD | cadmium sulfate promotes the reaction [HSF1 protein binds to HMOX1 promoter] | PMID:17244614 | | ||||||||||||||||||||||
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