GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hmox1 | multiple interactions | EXP | | 6480464 | CTD | [[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of HMOX1 mRNA] which results in increased chemical synthesis of Bilirubin; [cobaltiprotoporphyrin results in increased expression of HMOX1 protein] which results in increased abundance of Bilirubin | PMID:15226216 PMID:21401295 | Hmox1 | affects activity | ISO | HMOX1 (Homo sapiens) | 6480464 | CTD | Bilirubin affects the activity of HMOX1 protein | PMID:12690112 | Hmox1 | increases abundance | ISO | HMOX1 (Homo sapiens) | 6480464 | CTD | HMOX1 protein results in increased abundance of Bilirubin | PMID:15226216 | Hmox1 | increases chemical synthesis | ISO | HMOX1 (Homo sapiens) | 6480464 | CTD | HMOX1 protein results in increased chemical synthesis of Bilirubin | PMID:26968795 | Hmox1 | increases expression | ISO | HMOX1 (Homo sapiens) | 6480464 | CTD | Bilirubin results in increased expression of HMOX1 mRNA | PMID:20196124 | Hmox1 | multiple interactions | ISO | Hmox1 (Mus musculus) | 6480464 | CTD | [Rotenone co-treated with Bilirubin] inhibits the reaction [Cannabidiol results in increased expression of HMOX1 mRNA]; Bilirubin inhibits the reaction [Cannabidiol results in increased expression of HMOX1 mRNA]; sodium arsenite promotes the reaction [HMOX1 protein results in increased chemical synthesis of Bilirubin] | PMID:22688006 PMID:32033040 | Hmox1 | multiple interactions | ISO | HMOX1 (Homo sapiens) | 6480464 | CTD | [Ethanol results in increased expression of HMOX1 protein] which results in increased abundance of Bilirubin; Atazanavir Sulfate promotes the reaction [HMOX1 protein results in increased chemical synthesis of Bilirubin]; Bilirubin inhibits the reaction [[tin protoporphyrin IX results in decreased activity of HMOX1 protein] which results in increased chemical synthesis of Reactive Oxygen Species]; Bilirubin inhibits the reaction [Ritonavir results in increased expression of HMOX1 protein]; Lopinavir promotes the reaction [HMOX1 protein results in increased chemical synthesis of Bilirubin]; Ritonavir promotes the reaction [HMOX1 protein results in increased chemical synthesis of Bilirubin] | PMID:12690112 PMID:15602829 PMID:26968795 | |
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