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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2801
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hmbs
Name: hydroxymethylbilane synthase
Acc ID: CHEBI:78782
Term: pyrrolidine dithiocarbamate
Definition: A member of the class of dithiocarbamic acids that is the N-dithiocarboxy derivative of pyrrolidine.
Chemical ID: MESH:C020972
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hmbsmultiple interactionsISOHMBS (Homo sapiens)6480464CTDpyrrolidine dithiocarbamic acid inhibits the reaction [Aclarubicin results in increased expression of HMBS mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Butyric Acid results in increased expression of HMBS mRNA]PMID:10656287
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