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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2797
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hk2
Name: hexokinase 2
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hk2affects expressionISOHK2 (Homo sapiens)6480464CTDOxygen deficiency affects the expression of HK2 proteinPMID:34900531
Hk2affects expressionISOHk2 (Mus musculus)6480464CTDOxygen deficiency affects the expression of HK2 mRNAPMID:17193925
Hk2increases expressionISOHK2 (Homo sapiens)6480464CTDOxygen deficiency results in increased expression of HK2 mRNA; Oxygen deficiency results in increased expression of HK2 proteinPMID:19502547 PMID:20042640 PMID:24236059 PMID:26087400 PMID:30381462
Hk2multiple interactionsISOHK2 (Homo sapiens)6480464CTDbruceine D affects the reaction [Oxygen deficiency affects the expression of HK2 protein]; CTNNBIP1 protein affects the reaction [bruceine D affects the reaction [Oxygen deficiency affects the expression of HK2 protein]]PMID:34900531
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