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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2783
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hbb
Name: hemoglobin subunit beta
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hbbaffects expressionEXP 6480464CTDbisphenol A affects the expression of HBB mRNA; bisphenol A affects the expression of HBB-B1 mRNAPMID:25181051 PMID:30816183 PMID:30903817 PMID:32145629
Hbbdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of HBB protein; bisphenol A results in decreased expression of HBB-B1 mRNA; bisphenol A results in decreased expression of HBB-B1 proteinPMID:24552547 PMID:30816183 PMID:32145629
Hbbincreases expressionEXP 6480464CTDbisphenol A results in increased expression of HBB mRNA; bisphenol A results in increased expression of HBB-B1 mRNAPMID:27257137 PMID:33296240
Hbbdecreases expressionISOHBB (Homo sapiens)6480464CTDbisphenol A results in decreased expression of HBB proteinPMID:31675489
Hbbincreases expressionISOHbb-b1 (Mus musculus)6480464CTDbisphenol A results in increased expression of HBB mRNA; bisphenol A results in increased expression of HBB-B1 proteinPMID:24465770 PMID:28641223
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