GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gstm1 | increases expression | EXP | | 6480464 | CTD | Pregnenolone Carbonitrile results in increased expression of GSTM1 mRNA | PMID:19162173 | Gstm1 | increases expression | ISO | Gstm1 (Mus musculus) | 6480464 | CTD | Pregnenolone Carbonitrile results in increased expression of GSTM1 mRNA | PMID:18723825 PMID:22496397 PMID:27413110 PMID:28903501 | Gstm1 | multiple interactions | ISO | Gstm1 (Mus musculus) | 6480464 | CTD | [Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of GSTM1 mRNA; NR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of GSTM1 mRNA]; Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to GSTM1 5' UTR] | PMID:20693526 PMID:22496397 | | ||||||||||||||||||||||
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