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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2746
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Grm5
Name: glutamate metabotropic receptor 5
Acc ID: CHEBI:16015
Term: L-glutamic acid
Definition: An optically active form of glutamic acid having L-configuration.
Chemical ID: MESH:D018698
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Grm5affects response to substanceISOGrm5 (Mus musculus)6480464CTDGRM5 protein affects the susceptibility to Glutamic AcidPMID:27543109
Grm5multiple interactionsISOGrm5 (Mus musculus)6480464CTDGRM5 protein affects the reaction [[3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide co-treated with Glutamic Acid] results in increased phosphorylation of AKT1 protein]; GRM5 protein affects the reaction [[3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide co-treated with Glutamic Acid] results in increased phosphorylation of MAPK1 protein]; GRM5 protein affects the reaction [[3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide co-treated with Glutamic Acid] results in increased phosphorylation of MAPK3 protein]; GRM5 protein affects the reaction [[cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester co-treated with Glutamic Acid] results in increased phosphorylation of AKT1 protein]; GRM5 protein affects the reaction [[cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester co-treated with Glutamic Acid] results in increased phosphorylation of MAPK1 protein]; GRM5 protein affects the reaction [[cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester co-treated with Glutamic Acid] results in increased phosphorylation of MAPK3 protein]; GRM5 protein affects the reaction [[JZL 184 co-treated with Glutamic Acid] results in increased phosphorylation of AKT1 protein]; GRM5 protein affects the reaction [[JZL 184 co-treated with Glutamic Acid] results in increased phosphorylation of MAPK1 protein]; GRM5 protein affects the reaction [[JZL 184 co-treated with Glutamic Acid] results in increased phosphorylation of MAPK3 protein]; GRM5 protein affects the reaction [Glutamic Acid results in increased phosphorylation of AKT1 protein]; GRM5 protein affects the reaction [Glutamic Acid results in increased phosphorylation of MAPK1 protein]; GRM5 protein affects the reaction [Glutamic Acid results in increased phosphorylation of MAPK3 protein]PMID:27543109
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