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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2741
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr3c1
Name: nuclear receptor subfamily 3, group C, member 1
Acc ID: CHEBI:84070
Term: sodium arsenate
Definition: An inorganic sodium salt composed from sodium cations and arsenate anions in a 3:1 ratio.
Chemical ID: MESH:C009277
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr3c1affects expressionISONr3c1 (Mus musculus)6480464CTDsodium arsenate affects the expression of NR3C1 proteinPMID:24952232
Nr3c1affects localizationISONr3c1 (Mus musculus)6480464CTDsodium arsenate affects the localization of NR3C1 proteinPMID:22960421
Nr3c1decreases expressionISONr3c1 (Mus musculus)6480464CTDsodium arsenate results in decreased expression of NR3C1 proteinPMID:29132937
Nr3c1increases expressionISONr3c1 (Mus musculus)6480464CTDsodium arsenate results in increased expression of NR3C1 mRNAPMID:21795629
Nr3c1multiple interactionsISONr3c1 (Mus musculus)6480464CTDFluoxetine affects the reaction [sodium arsenate affects the expression of NR3C1 protein]; sodium arsenate inhibits the reaction [NR3C1 protein binds to GAS5 mRNA]PMID:24952232 PMID:29132937
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