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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2738
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Grin2b
Name: glutamate ionotropic receptor NMDA type subunit 2B
Acc ID: CHEBI:3374
Term: capsaicin
Definition: A capsaicinoid that has formula C18H27NO3.
Chemical ID: MESH:D002211
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Grin2bincreases phosphorylationEXP 6480464CTDCapsaicin results in increased phosphorylation of GRIN2B proteinPMID:18577691
Grin2bmultiple interactionsEXP 6480464CTDcapsazepine inhibits the reaction [Capsaicin results in increased phosphorylation of GRIN2B protein]; Excitatory Amino Acid Antagonists inhibits the reaction [Capsaicin results in increased phosphorylation of GRIN2B protein]PMID:18577691
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