GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gpx1 | decreases activity | EXP | | 6480464 | CTD | Streptozocin results in decreased activity of GPX1 protein | PMID:30318971 | Gpx1 | decreases expression | EXP | | 6480464 | CTD | Streptozocin results in decreased expression of GPX1 mRNA | PMID:23267840 PMID:24740756 PMID:33639173 | Gpx1 | increases expression | EXP | | 6480464 | CTD | Streptozocin results in increased expression of GPX1 protein | PMID:19634143 | Gpx1 | multiple interactions | EXP | | 6480464 | CTD | [[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of GPX1 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of GPX1 mRNA; [Carbamazepine affects the susceptibility to [Dietary Fats co-treated with Streptozocin]] which results in decreased expression of GPX1 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of GPX1 mRNA; allyl methyl sulfide inhibits the reaction [Streptozocin results in decreased activity of GPX1 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; Trientine inhibits the reaction [Streptozocin results in increased expression of GPX1 protein] | PMID:19634143 PMID:23267840 PMID:24740756 PMID:30318971 PMID:33639173 PMID:35786680 | Gpx1 | decreases activity | ISO | Gpx1 (Mus musculus) | 6480464 | CTD | Streptozocin results in decreased activity of GPX1 protein | PMID:18789669 | Gpx1 | decreases expression | ISO | Gpx1 (Mus musculus) | 6480464 | CTD | Streptozocin results in decreased expression of GPX1 mRNA | PMID:18789669 | Gpx1 | multiple interactions | ISO | Gpx1 (Mus musculus) | 6480464 | CTD | [Dietary Fats co-treated with Streptozocin] results in decreased expression of GPX1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of GPX1 protein; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of GPX1 protein]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GPX1 mRNA]; Sodium Selenite inhibits the reaction [Streptozocin results in decreased activity of GPX1 protein]; Sodium Selenite inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA] | PMID:18789669 PMID:33359794 PMID:37482253 | | ||||||||||||||||||||||
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