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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2729
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gpx1
Name: glutathione peroxidase 1
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gpx1affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of GPX1 mRNAPMID:12225545 PMID:34747641
Gpx1decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of GPX1 mRNAPMID:18465118 PMID:18796159 PMID:32109520
Gpx1increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of GPX1 mRNAPMID:33387578
Gpx1affects expressionISOGpx1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of GPX1 mRNAPMID:21570461
Gpx1decreases expressionISOGpx1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of GPX1 mRNAPMID:18467041
Gpx1increases expressionISOGpx1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of GPX1 mRNAPMID:21041162
Gpx1multiple interactionsISOGpx1 (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GPX1 mRNAPMID:17942748
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