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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2729
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gpx1
Name: glutathione peroxidase 1
Acc ID: CHEBI:28714
Term: S-butyl-DL-homocysteine (S,R)-sulfoximine
Definition: A sulfoximide that is the sulfoximine derivative of an analogue of DL-methionine in which the S-methyl group is replaced by S-butyl.
Chemical ID: MESH:D019328
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gpx1multiple interactionsEXP 6480464CTDButhionine Sulfoximine promotes the reaction [Microcystins analog results in increased expression of GPX1 mRNA]PMID:24964298
Gpx1affects activityISOGpx1 (Mus musculus)6480464CTDButhionine Sulfoximine affects the activity of GPX1 proteinPMID:15707499
Gpx1multiple interactionsISOGPX1 (Homo sapiens)6480464CTDButhionine Sulfoximine promotes the reaction [pterostilbene results in increased expression of GPX1 mRNA]PMID:25341683
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