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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2711
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc2a4
Name: solute carrier family 2 member 4
Acc ID: CHEBI:64243
Term: monosodium L-glutamate
Definition: An optically active form of monosodium glutamate having L-configuration.
Chemical ID: MESH:D012970
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc2a4affects expressionEXP 6480464CTDSodium Glutamate affects the expression of SLC2A4 mRNA; Sodium Glutamate affects the expression of SLC2A4 proteinPMID:31077719
Slc2a4decreases expressionEXP 6480464CTDSodium Glutamate results in decreased expression of SLC2A4 proteinPMID:11319642
Slc2a4multiple interactionsEXP 6480464CTDCarbenoxolone affects the reaction [Sodium Glutamate affects the expression of SLC2A4 mRNA]; Carbenoxolone affects the reaction [Sodium Glutamate affects the expression of SLC2A4 protein]PMID:31077719
Slc2a4decreases expressionISOSlc2a4 (Mus musculus)6480464CTDSodium Glutamate results in decreased expression of SLC2A4 mRNA; Sodium Glutamate results in decreased expression of SLC2A4 proteinPMID:19800637 PMID:22415589 PMID:25834641 PMID:28708105 PMID:29679905
Slc2a4increases expressionISOSlc2a4 (Mus musculus)6480464CTDSodium Glutamate results in increased expression of SLC2A4 proteinPMID:22415589
Slc2a4multiple interactionsISOSlc2a4 (Mus musculus)6480464CTDAtorvastatin inhibits the reaction [Sodium Glutamate results in decreased expression of SLC2A4 mRNA]; Atorvastatin inhibits the reaction [Sodium Glutamate results in decreased expression of SLC2A4 protein]; Atorvastatin inhibits the reaction [Sodium Glutamate results in increased expression of SLC2A4 mRNA]; Atorvastatin inhibits the reaction [Sodium Glutamate results in increased expression of SLC2A4 protein]; Resveratrol inhibits the reaction [Sodium Glutamate results in decreased expression of SLC2A4 mRNA]; Resveratrol inhibits the reaction [Sodium Glutamate results in decreased expression of SLC2A4 protein]; Tea inhibits the reaction [Sodium Glutamate results in decreased expression of SLC2A4 protein]PMID:19800637 PMID:25834641 PMID:28708105 PMID:29679905
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