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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2686
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gh1
Name: growth hormone 1
Acc ID: CHEBI:6503
Term: lisinopril dihydrate
Definition: A hydrate that has formula C21H35N3O7.
Chemical ID: MESH:D017706
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gh1multiple interactionsEXP 6480464CTD[Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in decreased expression of TIMP1 protein]; [Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in increased expression of MMP2 protein]; [Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in increased expression of NOS2 mRNA]PMID:20051877
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