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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2679
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gfap
Name: glial fibrillary acidic protein
Acc ID: CHEBI:28216
Term: methylmercury chloride
Definition: A chlorine molecular entity that has formula CH3ClHg.
Chemical ID: MESH:C004925
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gfapincreases expressionEXP 6480464CTDmethylmercuric chloride results in increased expression of GFAP mRNA; methylmercuric chloride results in increased expression of GFAP proteinPMID:28821999 PMID:30890323 PMID:31378766
Gfapmultiple interactionsEXP 6480464CTDfisetin inhibits the reaction [methylmercuric chloride results in increased expression of GFAP protein]PMID:30890323
Gfapaffects expressionISOGfap (Mus musculus)6480464CTDmethylmercuric chloride affects the expression of GFAP proteinPMID:33301842
Gfapincreases expressionISOGFAP (Homo sapiens)6480464CTDmethylmercuric chloride results in increased expression of GFAP mRNAPMID:27729293
Gfapmultiple interactionsISOGfap (Mus musculus)6480464CTD[GHRL protein co-treated with methylmercuric chloride] affects the expression of GFAP proteinPMID:33301842
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