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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2668
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gcg
Name: glucagon
Acc ID: CHEBI:15756
Term: hexadecanoic acid
Definition: A straight-chain, sixteen-carbon, saturated long-chain fatty acid.
Chemical ID: MESH:D019308
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gcgmultiple interactionsISOGcg (Mus musculus)6480464CTD[GCG protein co-treated with candesartan] inhibits the reaction [Palmitic Acid results in decreased phosphorylation of FOXO1 protein]; [GCG protein co-treated with candesartan] inhibits the reaction [Palmitic Acid results in decreased phosphorylation of IRS2 protein]; GCG protein inhibits the reaction [Palmitic Acid results in decreased phosphorylation of FOXO1 protein]; GCG protein inhibits the reaction [Palmitic Acid results in decreased phosphorylation of IRS2 protein]; isosteviol inhibits the reaction [Palmitic Acid promotes the reaction [Glucose results in increased secretion of GCG protein]]; Palmitic Acid promotes the reaction [Glucose results in increased secretion of GCG protein]PMID:21255808 PMID:22479612
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