GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gadd45a | affects expression | ISO | Gadd45a (Mus musculus) | 6480464 | CTD | Tamoxifen affects the expression of GADD45A mRNA | PMID:20937368 | Gadd45a | decreases expression | ISO | Gadd45a (Mus musculus) | 6480464 | CTD | Tamoxifen results in decreased expression of GADD45A mRNA | PMID:25123088 | Gadd45a | increases expression | ISO | GADD45A (Homo sapiens) | 6480464 | CTD | Tamoxifen results in increased expression of GADD45A mRNA | PMID:15604281 PMID:20549698 | Gadd45a | multiple interactions | ISO | GADD45A (Homo sapiens) | 6480464 | CTD | Tamoxifen inhibits the reaction [EGF protein results in increased expression of GADD45A mRNA]; TP53 protein promotes the reaction [Tamoxifen results in increased expression of GADD45A mRNA] | PMID:20549698 PMID:24758408 | |
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