Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2645
Species: Rattus norvegicus
RGD Object: Gene
Symbol: G6pd
Name: glucose-6-phosphate dehydrogenase
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
G6pdaffects expressionEXP 6480464CTDAcetaminophen affects the expression of G6PDX mRNA; Acetaminophen affects the expression of G6PDX proteinPMID:15800402 PMID:18246545
G6pddecreases expressionEXP 6480464CTDAcetaminophen results in decreased expression of G6PDX mRNAPMID:18246545
G6pdincreases expressionEXP 6480464CTDAcetaminophen results in increased expression of G6PDX mRNAPMID:17202762
G6pdaffects expressionISOG6pdx (Mus musculus)6480464CTDAcetaminophen affects the expression of G6PDX mRNAPMID:17562736
G6pdincreases expressionISOG6pdx (Mus musculus)6480464CTDAcetaminophen results in increased expression of G6PDX mRNAPMID:29246445
G6pdincreases expressionISOG6PD (Homo sapiens)6480464CTDAcetaminophen results in increased expression of G6PD mRNA; Acetaminophen results in increased expression of G6PD proteinPMID:22230336 PMID:25399406
G6pdmultiple interactionsISOG6pdx (Mus musculus)6480464CTDPANX1 gene mutant form inhibits the reaction [Acetaminophen results in increased expression of G6PDX mRNA]PMID:29246445
Go Back to source page   Continue to Ontology report