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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2644
Species: Rattus norvegicus
RGD Object: Gene
Symbol: G6pc1
Name: glucose-6-phosphatase catalytic subunit 1
Acc ID: CHEBI:34317
Term: 3,3',4,4',5-pentachlorobiphenyl
Definition: A pentachlorobiphenyl in which the chlorines are located at the 3, 4, 5, 3', and 4' positions.
Chemical ID: MESH:C023035
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
G6pc1decreases expressionEXP 6480464CTD3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of G6PC1 mRNAPMID:27509375 PMID:29474705 PMID:34848246
G6pc1multiple interactionsEXP 6480464CTDAHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of G6PC1 mRNA]PMID:34848246
G6pc1decreases expressionISOG6pc1 (Mus musculus)6480464CTD3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of G6PC1 mRNAPMID:30312631
G6pc1multiple interactionsISOG6pc1 (Mus musculus)6480464CTD3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in decreased expression of G6PC1 mRNA]; [Methionine deficiency co-treated with Choline deficiency co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in decreased expression of G6PC1 mRNA; aroclor 1260 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of G6PC1 mRNA]PMID:28163111 PMID:30312631
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