Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2630
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fshb
Name: follicle stimulating hormone subunit beta
Acc ID: CHEBI:5132
Term: flutamide
Definition: A (trifluoromethyl)benzene that has formula C11H11F3N2O3.
Chemical ID: MESH:D005485
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fshbincreases expressionEXP 6480464CTDFlutamide results in increased expression of FSHB mRNA; Flutamide results in increased expression of FSHB proteinPMID:12377983 PMID:14967917 PMID:26485406
Fshbincreases expressionISOFshb (Mus musculus)6480464CTDFlutamide results in increased expression of FSHB mRNAPMID:34954075
Fshbmultiple interactionsISOFSHB (Homo sapiens)6480464CTD[LHRH, Ala(6)-Gly(10)-ethylamide- co-treated with Flutamide] results in decreased expression of FSHB proteinPMID:11228061
Go Back to source page   Continue to Ontology report