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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2626
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fos
Name: Fos proto-oncogene, AP-1 transcription factor subunit
Acc ID: CHEBI:31206
Term: ammonium chloride
Definition: An inorganic chloride having ammonium as the counterion.
Chemical ID: MESH:D000643
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fosaffects expressionEXP 6480464CTDAmmonium Chloride affects the expression of FOS mRNAPMID:16483693
Fosdecreases expressionEXP 6480464CTDAmmonium Chloride results in decreased expression of FOS mRNA; Ammonium Chloride results in decreased expression of FOS proteinPMID:17442060
Fosdecreases phosphorylationEXP 6480464CTDAmmonium Chloride results in decreased phosphorylation of FOS proteinPMID:17442060
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