GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Fn1 | increases expression | EXP | | 6480464 | CTD | Streptozocin results in increased expression of FN1; Streptozocin results in increased expression of FN1 mRNA; Streptozocin results in increased expression of FN1 protein | PMID:11798618 PMID:12140129 PMID:14586741 PMID:16973718 PMID:19895808 PMID:21300041 PMID:21450970 PMID:21998146 PMID:22228707 PMID:22733486 PMID:23376009 PMID:23611540 PMID:24413998 PMID:25057273 PMID:25301743 PMID:31009641 | Fn1 | multiple interactions | EXP | | 6480464 | CTD | 3-aminobenzamide inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; [Streptozocin co-treated with Cadmium] results in increased expression of FN1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein; Aspirin inhibits the reaction [Streptozocin results in increased expression of FN1]; benazepril inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; Carvedilol inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; esculetin inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; esculetin inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; fenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of FN1 protein]; Organoselenium Compounds inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; stannous mesoporphyrin inhibits the reaction [4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased expression of FN1 protein]]; Trientine inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; XLF-III-43 inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA] | PMID:11798618 PMID:12140129 PMID:14586741 PMID:16973718 PMID:19895808 PMID:21300041 PMID:21450970 PMID:22228707 PMID:22733486 PMID:23376009 PMID:23611540 PMID:24413998 PMID:24877639 PMID:25057273 PMID:25240712 PMID:25301743 PMID:26341651 PMID:31009641 | Fn1 | increases expression | ISO | Fn1 (Mus musculus) | 6480464 | CTD | Streptozocin results in increased expression of FN1 mRNA; Streptozocin results in increased expression of FN1 protein | PMID:29420703 PMID:30184259 | Fn1 | multiple interactions | ISO | Fn1 (Mus musculus) | 6480464 | CTD | [AM6545 co-treated with Perindopril] inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein; [fatostatin co-treated with Streptozocin] results in increased expression of FN1 mRNA; [fatostatin co-treated with Streptozocin] results in increased expression of FN1 protein; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of FN1 protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of FN1 protein; AM6545 inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; CREB1 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]]; KLF15 gene mutant form promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]; Perindopril inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of FN1 protein] | PMID:27292126 PMID:29420703 PMID:30184259 PMID:34310909 PMID:38282657 | | ||||||||||||||||||||||
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