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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2609
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fgf2
Name: fibroblast growth factor 2
Acc ID: CHEBI:26710
Term: sodium chloride
Definition: An inorganic chloride salt having sodium(1+) as the counterion.
Chemical ID: MESH:D012965
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fgf2increases expressionISOFGF2 (Homo sapiens)6480464CTDSodium Chloride results in increased expression of FGF2 mRNAPMID:26800359
Fgf2increases secretionISOFGF2 (Homo sapiens)6480464CTDSodium Chloride results in increased secretion of FGF2 proteinPMID:26800359
Fgf2multiple interactionsISOFGF2 (Homo sapiens)6480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Sodium Chloride results in increased expression of FGF2 mRNA]; 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Sodium Chloride results in increased secretion of FGF2 protein]; Apigenin inhibits the reaction [Sodium Chloride results in increased expression of FGF2 mRNA]; Dactinomycin inhibits the reaction [Sodium Chloride results in increased expression of FGF2 mRNA]; Luteolin inhibits the reaction [Sodium Chloride results in increased expression of FGF2 mRNA]; NFAT5 protein affects the reaction [Sodium Chloride results in increased expression of FGF2 mRNA]; NFAT5 protein affects the reaction [Sodium Chloride results in increased secretion of FGF2 protein]; pyrazolanthrone inhibits the reaction [Sodium Chloride results in increased expression of FGF2 mRNA]; Quercetin inhibits the reaction [Sodium Chloride results in increased expression of FGF2 mRNA]; SB 203580 inhibits the reaction [Sodium Chloride results in increased expression of FGF2 mRNA]PMID:26800359
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