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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2609
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fgf2
Name: fibroblast growth factor 2
Acc ID: CHEBI:15553
Term: prostaglandin F2alpha
Definition: A prostaglandins Falpha that is prosta-5,13-dien-1-oic acid substituted by hydroxy groups at positions 9, 11 and 15. It is a naturally occurring prostaglandin used to induce labor.
Chemical ID: MESH:D015237
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fgf2affects localizationEXP 6480464CTDDinoprost affects the localization of FGF2 proteinPMID:15654655
Fgf2multiple interactionsEXP 6480464CTD1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Dinoprost affects the localization of FGF2 protein]; Cycloheximide inhibits the reaction [Dinoprost affects the localization of FGF2 protein]; Dinoprost affects the localization of [FGF2 protein binds to FGFR2 protein]; Dinoprost promotes the reaction [FGF2 protein binds to FGFR2 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Dinoprost affects the localization of FGF2 protein]PMID:15654655 PMID:16365892
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