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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2587
Species: Rattus norvegicus
RGD Object: Gene
Symbol: F3
Name: coagulation factor III, tissue factor
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
F3decreases expressionISOF3 (Homo sapiens)6480464CTDresveratrol results in decreased expression of F3 mRNAPMID:11858183 PMID:12871381
F3multiple interactionsISOF3 (Homo sapiens)6480464CTD[Resveratrol results in increased activity of SIRT1 protein] inhibits the reaction [TNF protein results in increased expression of F3 mRNA]; [Resveratrol results in increased activity of SIRT1 protein] inhibits the reaction [TNF protein results in increased expression of F3 protein]; Resveratrol inhibits the reaction [IL1B protein results in increased activity of and results in increased expression of F3 protein]; Resveratrol inhibits the reaction [IL1B protein results in increased activity of F3 protein]; Resveratrol inhibits the reaction [IL1B protein results in increased expression of F3 mRNA]; Resveratrol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased activity of F3 protein]; Resveratrol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of F3 mRNA]; Resveratrol inhibits the reaction [Lipopolysaccharides results in increased activity of F3 protein]; Resveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of F3]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of F3 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of F3 mRNA]; Resveratrol inhibits the reaction [TNF protein results in increased activity of and results in increased expression of F3 protein]; Resveratrol inhibits the reaction [TNF protein results in increased activity of F3 protein]; Resveratrol inhibits the reaction [TNF protein results in increased expression of F3 mRNA]PMID:11858183 PMID:12871381 PMID:20978007 PMID:9974427
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