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GENE - TERM ANNOTATION REPORT

RGD ID: 2532
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Edn1
Name: endothelin 1
Acc ID: GO:0007193
Term: adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
Definition: A G protein-coupled receptor signaling pathway in which the signal is transmitted via the inhibition of adenylyl cyclase activity and a subsequent decrease in the intracellular concentration of cyclic AMP (cAMP).
Definition Source(s): GOC:dph, GOC:mah, GOC:signaling, GOC:tb, ISBN:0815316194
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Edn1acts_upstream_of_or_withinISOEdn1 (Mus musculus)1624291RGDMGI:88121 PMID:15632412 PMID:2542249

PMID:15632412 PMID:2542249
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