GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nqo1 | increases expression | EXP | | 6480464 | CTD | Acrylamide results in increased expression of NQO1 mRNA; Acrylamide results in increased expression of NQO1 protein | PMID:28959563 PMID:29426002 | Nqo1 | multiple interactions | EXP | | 6480464 | CTD | 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Acrylamide results in increased expression of NQO1 mRNA]; pyrazolanthrone inhibits the reaction [Acrylamide results in increased expression of NQO1 mRNA]; U 0126 inhibits the reaction [Acrylamide results in increased expression of NQO1 mRNA] | PMID:29426002 | Nqo1 | decreases expression | ISO | NQO1 (Homo sapiens) | 6480464 | CTD | Acrylamide results in decreased expression of NQO1 mRNA | PMID:28159594 | Nqo1 | increases expression | ISO | Nqo1 (Mus musculus) | 6480464 | CTD | Acrylamide results in increased expression of NQO1 mRNA; Acrylamide results in increased expression of NQO1 protein | PMID:27836571 PMID:28526328 PMID:33872730 | Nqo1 | increases expression | ISO | NQO1 (Homo sapiens) | 6480464 | CTD | Acrylamide results in increased expression of NQO1 mRNA | PMID:32763439 | Nqo1 | multiple interactions | ISO | Nqo1 (Mus musculus) | 6480464 | CTD | [NLRP3 gene mutant form affects the susceptibility to Acrylamide] which results in increased expression of NQO1 protein | PMID:32014472 | Nqo1 | multiple interactions | ISO | NQO1 (Homo sapiens) | 6480464 | CTD | salvin inhibits the reaction [Acrylamide results in decreased expression of NQO1 mRNA] | PMID:28159594 | |
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