GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nqo1 | increases expression | EXP | | 6480464 | CTD | Glucose results in increased expression of NQO1 mRNA | PMID:29211853 | Nqo1 | multiple interactions | EXP | | 6480464 | CTD | [Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of NQO1 mRNA; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NQO1 mRNA; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NQO1 protein; diosmetin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NQO1 mRNA]; diosmetin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NQO1 protein]; GSK3B protein inhibits the reaction [MIR135A mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of NQO1 mRNA]]; MIR135A mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of NQO1 mRNA]; NFE2L2 protein affects the reaction [Glucose results in increased expression of NQO1 mRNA] | PMID:29211853 PMID:29719095 PMID:35191607 | Nqo1 | decreases expression | ISO | NQO1 (Homo sapiens) | 6480464 | CTD | Glucose results in decreased expression of NQO1 mRNA; Glucose results in decreased expression of NQO1 protein | PMID:37586544 | Nqo1 | increases expression | ISO | Nqo1 (Mus musculus) | 6480464 | CTD | Glucose results in increased expression of NQO1 mRNA; Glucose results in increased expression of NQO1 protein | PMID:17178593 PMID:33270355 | Nqo1 | increases expression | ISO | NQO1 (Homo sapiens) | 6480464 | CTD | Glucose deficiency results in increased expression of NQO1 protein | PMID:29649567 | Nqo1 | multiple interactions | ISO | Nqo1 (Mus musculus) | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [SMARCA4A protein promotes the reaction [Glucose results in increased expression of NQO1 protein]]; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NQO1 mRNA; MIR144 mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NQO1 mRNA]; NQO1 gene mutant form promotes the reaction [Glucose results in increased chemical synthesis of Hydrogen Peroxide]; SMARCA4A protein promotes the reaction [Glucose results in increased expression of NQO1 protein] | PMID:27558805 PMID:29457851 PMID:33270355 | Nqo1 | multiple interactions | ISO | NQO1 (Homo sapiens) | 6480464 | CTD | solanesol inhibits the reaction [Glucose results in decreased expression of NQO1 mRNA]; solanesol inhibits the reaction [Glucose results in decreased expression of NQO1 protein] | PMID:37586544 | | ||||||||||||||||||||||
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