GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp2c11 | decreases activity | EXP | | 6480464 | CTD | Sodium Glutamate results in decreased activity of CYP2C11 protein | PMID:7476908 PMID:8496838 | Cyp2c11 | decreases expression | EXP | | 6480464 | CTD | Sodium Glutamate results in decreased expression of CYP2C11 mRNA | PMID:8496838 | Cyp2c11 | increases expression | EXP | | 6480464 | CTD | Sodium Glutamate results in increased expression of CYP2C11 mRNA; Sodium Glutamate results in increased expression of CYP2C11 mRNA alternative form; Sodium Glutamate results in increased expression of CYP2C11 protein | PMID:11089541 PMID:25697375 PMID:7965769 | Cyp2c11 | multiple interactions | EXP | | 6480464 | CTD | [Sodium Glutamate co-treated with GH1 protein] results in decreased splicing of CYP2C11 mRNA; [Sodium Glutamate co-treated with GH1 protein] results in increased splicing of CYP2C11 mRNA; [Sodium Glutamate co-treated with GH1 protein] results in increased ubiquitination of CYP2C11 protein; GH1 protein affects the reaction [Sodium Glutamate results in decreased activity of CYP2C11 protein]; GH1 protein affects the reaction [Sodium Glutamate results in decreased expression of CYP2C11 mRNA]; GH1 protein inhibits the reaction [Sodium Glutamate results in decreased activity of CYP2C11 protein]; Sodium Glutamate inhibits the reaction [GH1 protein results in increased expression of CYP2C11 protein]; Sodium Glutamate results in increased expression of and affects the splicing of CYP2C11 mRNA alternative form; Sodium Glutamate results in increased expression of and results in decreased splicing of CYP2C11 mRNA; Sodium Glutamate results in increased expression of and results in increased activity of CYP2C11 protein | PMID:11089541 PMID:25697375 PMID:7476908 PMID:7965769 PMID:8496838 | | ||||||||||||||||||||||
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