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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2466
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2b1
Name: cytochrome P450, family 2, subfamily b, polypeptide 1
Acc ID: CHEBI:32687
Term: piperonyl butoxide
Definition: A benzodioxole that has formula C19H30O5.
Chemical ID: MESH:D010882
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2b1increases expressionEXP 6480464CTDPiperonyl Butoxide results in increased expression of CYP2B1 mRNAPMID:20735435
Cyp2b1multiple interactionsEXP 6480464CTD[Permethrin co-treated with Piperonyl Butoxide] results in increased expression of CYP2B1 mRNA; Piperonyl Butoxide inhibits the reaction [Permethrin results in increased expression of CYP2B1 mRNA]PMID:11377398
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