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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2466
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2b1
Name: cytochrome P450, family 2, subfamily b, polypeptide 1
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2b1multiple interactionsEXP 6480464CTDpirinixic acid promotes the reaction [Phenobarbital results in increased activity of CYP2B1 protein]; pirinixic acid promotes the reaction [Phenobarbital results in increased expression of CYP2B1 mRNA]PMID:18023279 PMID:19631232
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