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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2460
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp1b1
Name: cytochrome P450, family 1, subfamily b, polypeptide 1
Acc ID: CHEBI:30772
Term: butyric acid
Definition: A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.
Chemical ID: MESH:D020148
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp1b1multiple interactionsISOCyp1b1 (Mus musculus)6480464CTDButyric Acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]PMID:31621310
Cyp1b1multiple interactionsISOCYP1B1 (Homo sapiens)6480464CTDButyric Acid promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; Butyric Acid promotes the reaction [biochanin A results in increased expression of CYP1B1 mRNA]; Butyric Acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]PMID:27830268 PMID:30439556 PMID:31621310
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