A triazaacenaphthylene that is 2,2a,3,4,5,5a,6,7-octahydro-1H-1,8,8b-triazaacenaphthylene which is substituted at positions 3, 4, and 7 by methyl, sulfooxy, and (2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)(hydroxy)methyl groups, respectively (the 2aS,3R,4S,5aS,7R stereoisomer in which the carbon bearing the hydroxy group has R configuration). It is a cyanotoxin produced by several species of freshwater cyanobacteria, such as Aphanizomenon ovalisporum.
Chemical ID:
MESH:C089595
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
[4,4'-hexafluorisopropylidene diphenol co-treated with cylindrospermopsin] results in decreased expression of CYP1A1 mRNA; [bisphenol A co-treated with cylindrospermopsin] results in decreased expression of CYP1A1 mRNA; [bisphenol F co-treated with cylindrospermopsin] results in decreased expression of CYP1A1 mRNA; [bisphenol S co-treated with cylindrospermopsin] results in decreased expression of CYP1A1 mRNA; [cylindrospermopsin co-treated with 4,4'-hexafluorisopropylidene diphenol] results in increased expression of CYP1A1 mRNA; [cylindrospermopsin co-treated with bisphenol A] results in increased expression of CYP1A1 mRNA; [cylindrospermopsin co-treated with bisphenol F] results in increased expression of CYP1A1 mRNA; [cylindrospermopsin co-treated with bisphenol S] results in increased expression of CYP1A1 mRNA