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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2443
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cth
Name: cystathionine gamma-lyase
Acc ID: CHEBI:17561
Term: L-cysteine
Definition: An optically active form of cysteine having L-configuration.
Chemical ID: MESH:D003545
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cthmultiple interactionsEXP 6480464CTD[Mercuric Chloride co-treated with Cysteine] results in decreased activity of CTH protein; Cysteine analog promotes the reaction [[Lipopolysaccharides results in decreased expression of CTH protein] which results in decreased chemical synthesis of Hydrogen Sulfide]PMID:21308383 PMID:22093698
Cthmultiple interactionsISOCTH (Homo sapiens)6480464CTD[CTH protein co-treated with Cysteine] results in increased chemical synthesis of Hydrogen Sulfide; N-acetylpropargylglycine inhibits the reaction [[CTH protein co-treated with Cysteine] results in increased chemical synthesis of Hydrogen Sulfide]PMID:18029544
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