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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2426
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Csf3
Name: colony stimulating factor 3
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects expressionISORGD:7314166480464CTDTetrachlorodibenzodioxin affects the expression of CSF3 mRNA

PMID:26377647
increases expressionISORGD:13509556480464CTDTetrachlorodibenzodioxin results in increased expression of CSF3 mRNA

PMID:28351761
increases expressionISORGD:7314166480464CTDTetrachlorodibenzodioxin results in increased expression of CSF3 mRNA

PMID:12167310, PMID:14678569, PMID:19933214, PMID:22749964
multiple interactionsISORGD:7314166480464CTDTetrachlorodibenzodioxin promotes the reaction [tributyltin results in increased expression of CSF3 mRNA]

PMID:22749964
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.