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GENE - TERM ANNOTATION REPORT

RGD ID: 2375
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Col2a1
Name: collagen type II alpha 1 chain
Acc ID: GO:0097192
Term: extrinsic apoptotic signaling pathway in absence of ligand
Definition: The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with withdrawal of a ligand from a cell surface receptor, and ends when the execution phase of apoptosis is triggered.
Definition Source(s): GOC:mtg_apoptosis, PMID:15044679, PMID:20816705
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Col2a1acts_upstream_ofISOCol2a1 (Mus musculus)1624291RGDMGI:2152978 PMID:9299161

PMID:9299161
Col2a1involved_inIEAUniProtKB:P28481 or ensembl:ENSMUSP000000231231600115EnsemblGO_REF:0000107

GO_REF:0000107
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