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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2366
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcc2
Name: ATP binding cassette subfamily C member 2
Acc ID: CHEBI:50730
Term: montelukast
Definition: An aliphatic sulfide that has formula 586.18398.
Chemical ID: MESH:C093875
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc2multiple interactionsISOABCC2 (Homo sapiens)6480464CTDmontelukast inhibits the reaction [ABCC2 protein results in increased export of calcein AM]; montelukast inhibits the reaction [ABCC2 protein results in increased export of Paclitaxel]; montelukast inhibits the reaction [ABCC2 protein results in increased export of Saquinavir]PMID:19952419
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