GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Abcc2 | affects expression | ISO | ABCC2 (Homo sapiens) | 6480464 | CTD | Paclitaxel affects the expression of ABCC2 mRNA | PMID:20737486 | Abcc2 | affects response to substance | ISO | ABCC2 (Homo sapiens) | 6480464 | CTD | ABCC2 protein affects the susceptibility to Paclitaxel | PMID:15645438 | Abcc2 | affects transport | ISO | ABCC2 (Homo sapiens) | 6480464 | CTD | ABCC2 protein affects the transport of Paclitaxel | PMID:15849751 | Abcc2 | decreases response to substance | ISO | ABCC2 (Homo sapiens) | 6480464 | CTD | ABCC2 protein results in decreased susceptibility to Paclitaxel | PMID:15849751 | Abcc2 | increases export | ISO | ABCC2 (Homo sapiens) | 6480464 | CTD | ABCC2 protein results in increased export of Paclitaxel | PMID:19952419 | Abcc2 | increases expression | ISO | Abcc2 (Mus musculus) | 6480464 | CTD | Paclitaxel results in increased expression of ABCC2 mRNA; Paclitaxel results in increased expression of ABCC2 protein | PMID:28242239 | Abcc2 | multiple interactions | ISO | ABCC2 (Homo sapiens) | 6480464 | CTD | montelukast inhibits the reaction [ABCC2 protein results in increased export of Paclitaxel]; Probenecid promotes the reaction [ABCC2 protein affects the transport of Paclitaxel]; Probenecid promotes the reaction [ABCC2 protein results in decreased susceptibility to Paclitaxel]; verlukast inhibits the reaction [ABCC2 protein results in increased export of Paclitaxel] | PMID:15849751 PMID:19952419 | |
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