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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2347
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Chrna5
Name: cholinergic receptor nicotinic alpha 5 subunit
Acc ID: CHEBI:7035
Term: muscimol
Definition: A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
Chemical ID: MESH:D009118
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Chrna5multiple interactionsISOCHRNA5 (Homo sapiens)6480464CTDMuscimol binds to and results in increased activity of [CHRNA5 protein co-treated with CHRNB1 protein]PMID:8388298
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