GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cftr | multiple interactions | EXP | | 6480464 | CTD | CFTR protein promotes the reaction [Cyclic AMP results in increased transport of Chlorine]; Cyclic AMP affects the localization of and results in increased activity of CFTR protein; Nitric Oxide inhibits the reaction [CFTR protein promotes the reaction [Cyclic AMP results in increased transport of Chlorine]]; Nocodazole inhibits the reaction [Cyclic AMP affects the localization of and results in increased activity of CFTR protein]; Primaquine inhibits the reaction [Cyclic AMP affects the localization of and results in increased activity of CFTR protein] | PMID:12529251 PMID:12612912 | Cftr | increases activity | ISO | CFTR (Homo sapiens) | 6480464 | CTD | Cyclic AMP results in increased activity of CFTR protein | PMID:15229107 PMID:15371258 | Cftr | multiple interactions | ISO | Cftr (Mus musculus) | 6480464 | CTD | Genistein promotes the reaction [Cyclic AMP results in increased activity of CFTR protein mutant form] | PMID:12556293 | Cftr | multiple interactions | ISO | CFTR (Homo sapiens) | 6480464 | CTD | Cyclic AMP promotes the reaction [CFTR protein results in increased transport of Bicarbonates]; Cyclic AMP promotes the reaction [CFTR protein results in increased transport of Chlorides] | PMID:11786964 | | ||||||||||||||||||||||
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