GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cebpa | increases activity | ISO | CEBPA (Homo sapiens) | 6480464 | CTD | Tretinoin results in increased activity of CEBPA protein | PMID:16226872 | Cebpa | multiple interactions | ISO | Cebpa (Mus musculus) | 6480464 | CTD | Tretinoin inhibits the reaction [CEBPA protein binds to RETN promoter] | PMID:15047602 | Cebpa | multiple interactions | ISO | CEBPA (Homo sapiens) | 6480464 | CTD | PTK2 protein inhibits the reaction [Tretinoin promotes the reaction [CEBPA protein binds to RB1 protein]]; PTK2 protein inhibits the reaction [Tretinoin results in increased activity of CEBPA protein]; Tretinoin inhibits the reaction [CEBPA protein binds to ALB promoter]; Tretinoin promotes the reaction [CEBPA protein binds to MIR223 promoter]; Tretinoin promotes the reaction [CEBPA protein binds to RB1 protein]; Tretinoin promotes the reaction [CEBPA protein results in increased expression of MIR223 mRNA] | PMID:16226872 PMID:16325577 PMID:16608438 | |
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