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GENE - TERM ANNOTATION REPORT

RGD ID: 2325582
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mir96
Name: microRNA 96
Acc ID: DOID:4752
Term: multiple system atrophy
Definition: A syndrome complex composed of three conditions which represent clinical variants of the same disease process: STRIATONIGRAL DEGENERATION; SHY-DRAGER SYNDROME; and the sporadic form of OLIVOPONTOCEREBELLAR ATROPHIES. Clinical features include autonomic, cerebellar, and basal ganglia dysfunction. Pathologic examination reveals atrophy of the basal ganglia, cerebellum, pons, and medulla, with prominent loss of autonomic neurons in the brain stem and spinal cord. (From Adams et al., Principles of Neurology, 6th ed, p1076; Baillieres Clin Neurol 1997 Apr;6(1):187-204; Med Clin North Am 1999 Mar;83(2):381-92)
Definition Source(s): MESH:D019578
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mir96 ISOMIR96 (Homo sapiens)11553929RGDRNA:increased expression:frontal cortex: 
Mir96 ISOMir96 (Mus musculus)11553929RGDRNA:increased expression:frontal cortex: 
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