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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2325581
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mir98
Name: microRNA 98
Acc ID: CHEBI:18723
Term: nicotine
Definition: A racemate composed of equimolar amounts of (R)- and (S)-nicotine.
Chemical ID: MESH:D009538
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mir98decreases expressionISOMIR98 (Homo sapiens)6480464CTDNicotine results in decreased expression of MIR98 mRNAPMID:33082140
Mir98decreases expressionISOMir98 (Mus musculus)6480464CTDNicotine results in decreased expression of MIR98 mRNAPMID:33082140
Mir98multiple interactionsISOMir98 (Mus musculus)6480464CTDMIR98 mRNA affects the reaction [Nicotine results in increased expression of NGF protein]; MIR98 mRNA inhibits the reaction [Nicotine results in increased expression of EDN1 mRNA]; MIR98 mRNA inhibits the reaction [Nicotine results in increased expression of FN1 mRNA]; Rosiglitazone inhibits the reaction [Nicotine results in decreased expression of MIR98 mRNA]PMID:33082140
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