GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mir125b1 | increases expression | ISO | Mir125b-1 (Mus musculus) | 6480464 | CTD | carvedilol results in increased expression of MIR125B-1 mRNA | PMID:24334028 | Mir125b1 | multiple interactions | ISO | MIR125B1 (Homo sapiens) | 6480464 | CTD | [carvedilol co-treated with ARRB1 protein] results in increased expression of MIR125B-1 mRNA | PMID:24334028 | Mir125b1 | multiple interactions | ISO | Mir125b-1 (Mus musculus) | 6480464 | CTD | ARRB1 gene mutant form inhibits the reaction [carvedilol results in increased expression of MIR125B-1 mRNA]; GRK5 gene mutant form inhibits the reaction [carvedilol results in increased expression of MIR125B-1 mRNA]; GRK6 gene mutant form inhibits the reaction [carvedilol results in increased expression of MIR125B-1 mRNA] | PMID:24334028 | |
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