Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - TERM ANNOTATION REPORT

RGD ID: 2324133
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdkl5
Name: cyclin-dependent kinase-like 5
Acc ID: DOID:1059
Term: intellectual disability
Definition: A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills. (DO)
Definition Source(s): http://aaidd.org/intellectual-disability/definition#.WsPDT2VvqaU "DO" "DO", https://en.wikipedia.org/wiki/Intellectual_disability "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdkl5 ISOCDKL5 (Homo sapiens)11053436RGDDNA:duplication: : 
Cdkl5 ISOCDKL5 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Intellectual disabilityPMID:18809835 PMID:19362436 PMID:19793311 PMID:21770923 PMID:22430159 PMID:22670135 PMID:22678952 PMID:22872100 PMID:25657822 PMID:25741868 PMID:26271793 PMID:26482601 PMID:26993267 PMID:28492532 PMID:29100083 PMID:30182498 PMID:30460546
Go Back to source page   Continue to Ontology report