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GENE - TERM ANNOTATION REPORT

RGD ID: 2321145
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fbxw7
Name: F-box and WD repeat domain containing 7
Acc ID: GO:0030332
Term: cyclin binding
Definition: Binding to cyclins, proteins whose levels in a cell varies markedly during the cell cycle, rising steadily until mitosis, then falling abruptly to zero. As cyclins reach a threshold level, they are thought to drive cells into G2 phase and thus to mitosis.
Definition Source(s): GOC:ai
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fbxw7enablesISOFBXW7 (Homo sapiens)1624291RGDUniProtKB:P24864 PMID:12628165 PMID:17434132

PMID:12628165 PMID:17434132
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