Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2316
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cd8a
Name: CD8 subunit alpha
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cd8aaffects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of CD8A mRNAPMID:34747641
Cd8adecreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of CD8A mRNAPMID:32109520
Cd8adecreases expressionISOCd8a (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of CD8A proteinPMID:14718643 PMID:15972635 PMID:20715097 PMID:9630460
Cd8adecreases expressionISOCD8A (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of CD8A mRNAPMID:19684285
Cd8amultiple interactionsISOCd8a (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CD8A mRNA; resveratrol inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CD8A protein]PMID:17942748 PMID:20715097
Cd8amultiple interactionsISOCD8A (Homo sapiens)6480464CTD[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of CD8A mRNAPMID:19684285
Go Back to source page   Continue to Ontology report