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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2313363
Species: Mus musculus
RGD Object: Gene
Symbol: Sprr2a2
Name: small proline-rich protein 2A2
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sprr2a2increases expressionEXP 6480464CTDOzone results in increased expression of SPRR2A2 mRNAPMID:31626304 PMID:33026818
Sprr2a2multiple interactionsEXP 6480464CTD[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of SPRR2A2 mRNA; [Air Pollutants results in increased abundance of Ozone] which results in increased expression of SPRR2A2 mRNAPMID:34911549
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